The Tonight Show with Conan O'Brien

Will Ferrell, Pearl Jam

The Tonight Show with Conan O'Brien kicks it off with actor/comedian Will Ferrell and musical guest Pearl Jam.

Tom Hanks, Green Day

The Tonight Show with Conan O'Brien welcomes actor Tom Hanks and musical guest Green Day.

Julia Louis-Dreyfus, Bradley Cooper, Sheryl Crow

The Tonight Show with Conan O'Brien welcomes actress Julia Louis-Dreyfus, actor Bradley Cooper and musical guest Sheryl

Gwyneth Paltrow, Joel McHale, John Mayer Trio

The Tonight Show with Conan O'Brien welcomes actress Gwyneth Paltrow, The Soup host Joel McHale and musical guest John M

Ryan Seacrest, Patton Oswalt, Chickenfoot

The Tonight Show with Conan O'Brien welcomes Ryan Seacrest, comedian Patton Oswalt and musical guests Chickenfoot.

David Duchovny, Anna Friel, Bill Burr

The Tonight Show with Conan O'Brien welcomes actor David Duchovny and Anna Friel. Comedian Bill Burr performs.

Eddie Murphy, Angela Kinsey, Bonnie Raitt & Taj Mahal

The Tonight Show with Conan O'Brien welcomes actor Eddie Murphy, Angela Kinsey and musical guest Bonnie Raitt & Taj Maha

Dane Cook, Steven Ho, Rancid

The Tonight Show with Conan O'Brien welcomes comedian Dane Cook, Steven Ho and musical guest Rancid.

Norm MacDonald, Jim Gaffigan, Neko Case

The Tonight Show welcomes comedian Norm MacDonald, comedian Jim Gaffigan and musical guest Neko Case.

Jamie Foxx, Kevin Nealon

The Tonight Show with Conan O'Brien welcomes actor/singer Jamie Foxx and comedian Kevin Nealon. Music performed by Jamie

Joe Torre, Will Arnett, Spinal Tap

The Tonight Show with Conan O'Brien welcomes Dodgers manager Joe Torre, actor Will Arnett and musical guest Spinal Tap.

Larry David, Lauren Conrad, Gavin Rossdale

The Tonight Show with Conan O'Brien welcomes actor/writer Larry David, Lauren Conrad and musical guest Gavin Rossdale.

Kobe Bryant, William Shatner, Incubus

The Tonight Show with Conan O'Brien welcomes basketball star Kobe Bryant, actor William Shatner and musical guests Incub

Eva Mendes, Christopher Mintz-Plasse, The Dead Weather

The Tonight Show with Conan O'Brien welcomes guests Eva Mendes, Christopher Mintz-Plasse and musical guests The Dead Wea

Shia LaBeouf, Phil Jackson, Holly Williams

The Tonight Show with Conan O'Brien welcomes actor Shia LaBeouf, L.A. Lakers' coach Phil Jackson and musical guest Holly

Cameron Diaz, Johnny Strange, Pete Yorn

The Tonight Show with Conan O'Brien welcomes guests Cameron Diaz, Johnny Strange and musical guest Pete Yorn.

Lisa Kudrow, Billy Mays & Anthony Sullivan, Elvis Costello

The Tonight Show with Conan O'Brien welcomes guests Lisa Kudrow, Billy Mays & Anthony Sullivan and musical guest Elvis C

Brandon McMillan, Kerry Washington, Wilco

The Tonight Show with Conan O'Brien welcomes guests Brandon McMillon, Kerry Washington and musical guests Wilco.

Bruno, Stephen Moyer, Cirque du Soleil Zumanity

The Tonight Show with Conan O'Brien welcomes guests Bruno, Stephen Moyer and a closing performance by Cirque du Soleil Z

Snoop Dogg, Jerry Ferrara, Adele

The Tonight Show with Conan O'Brien welcomes guests Snoop Dogg, Jerry Ferrara and musical guest Adele.

Howie Mandel, Alanis Morissette, Death Cab for Cutie

The Tonight Show with Conan O'Brien welcomes actor/game show host Howie Mandel, singer Alanis Morissette, and musical pe

Samuel L. Jackson, Kevin Connolly, Andrew Bird

The Tonight Show with Conan O'Brien welcomes as guests actor Samuel L. Jackson, actor Kevin Connolly and musical guest A

Meredith Vieira, Andy Hillstrand, Al Madrigal

The Tonight Show with Conan O'Brien welcomes as guests from the The Today Show Meredith Vieira, from Deadliest Catch Cap

Larry King, Zooey Deschanel, Playing For Change

The Tonight Show with Conan O'Brien welcomes legendary TV host Larry King, actress Zooey Deschanel and musical guests Pl

Bob Newhart, Cat Deeley, Ray LaMontagne

The Tonight Show with Conan O'Brien welcomes comedy great Bob Newhart, from So You Think You Can Dance TV show host Cat

Jeff Goldblum, Bill Engvall, the cast of "Hair"

The Tonight Show with Conan O'Brien welcomes guest actor from Law & Order: Criminal Intent Jeff Goldblum, comedian Bill

Michael Phelps, Paget Brewster, Sugar Ray

The Tonight Show with Conan O'Brien welcomes swimming champion Michael Phelps, actress Paget Brewster and musical guests

Dana Carvey, Anthony Anderson, Allison Iraheta

The Tonight Show with Conan O'Brien welcomes actor Dana Carvey, Anthony Anderson and musical performance by Allison Irah

Gerard Butler, Venus Williams, Daughtry

The Tonight Show with Conan O'Brien welcomes actor Gerard Butler, tennis player Venus Williams and musical performance b

Steven Ho, Seth Green, Demi Lovato

The Tonight Show with Conan O'Brien welcomes guest actor Seth Green, Steven Ho and musical guest Demi Lovato.

Adam Sandler, Peter Sarsgaard, Kate Voegele

The Tonight Show with Conan O'Brien welcomes guest actors Adam Sandler, Peter Sarsgaard and musical guest Kate Voegele.

Jonah Hill, Cheryl Hines, Dan Naturman

The Tonight Show with Conan O'Brien welcomes guest actor Jonah Hill, actress Cheryl Hines, and comic Dan Naturman.

James Spader, Jack McBrayer, Mat Kearney

The Tonight Show with Conan O'Brien welcomes guest actors James Spader and Jack McBrayer and musical guest Mat Kearney.

Zach Galifianakis, Keke Palmer, Jason Aldean

The Tonight Show with Conan O'Brien welcomes comedian Zach Galifianakis, actress Keke Palmer and musical guest Jason Ald

Seth Rogen, Rose Byrne, Eric Hutchinson

The Tonight Show with Conan O'Brien welcomes actor Seth Rogen, actress Rose Byrne, and musical guest Eric Hutchinson.

Meryl Streep, Judd Apatow, the Fray

The Tonight Show with Conan O'Brien welcomes actress Meryl Streep, film director/producer/writer Judd Apatow and musical

Heidi Klum, Steve Zahn, Jimmy Carr

The Tonight Show with Conan O'Brien welcomes supermodel Heidi Klum, actor Steve Zahn and British comedian Jimmy Carr.

Rainn Wilson, Rachel Maddow, Chicago

The Tonight Show with Conan O'Brien welcomes actor Rainn Wilson, radio personality Rachel Maddow and musical guests Chic

Paul Giamatti, Jack Dagger, Tonya Kay, Regina Spektor

The Tonight Show with Conan O'Brien welcomes Jack Dagger & Tonya Kay, actor Paul Giamatti and musical guest Regina Spekt

Hank Azaria, Adam Richman, Ben Harper & Relentless7

The Tonight Show with Conan O'Brien welcomes actor Hank Azaria, host of "Man v. Food" Adam Richman and musical guest Ben

Ashton Kutcher, Charlyne Yi, Gomez

The Tonight Show with Conan O'Brien welcomes actor Ashton Kutcher, actress Charlyne Yi, and musical guest Gomez.

Jeremy Piven, the Human Cannonballs, All-American Rejects

The Tonight Show with Conan O'Brien welcomes actor Jeremy Piven, The Human Cannonballs and musical guests the All-Americ

Sienna Miller, Steve Schirripa, Deon Cole

The Tonight Show with Conan O'Brien welcomes actress Sienna Miller, actor and TV show host Steve Schirripa, and a perfor

Jonas Brothers, Ed Helms

The Tonight Show with Conan O'Brien welcomes actor Ed Helms and The Jonas Brothers. Both Ed Helms and The Jonas Brothers

Eric Bana, Mary Lynn Rajskub, Flo Rida

The Tonight Show with Conan O'Brien welcomes Eric Bana, Mary Lynn Rajskub and musical guest Flo Rida.

Kyra Sedgwick, Hugh Dancy, Lyle Lovett and His Large Band

The Tonight Show with Conan O'Brien welcomes Kyra Sedgwick, Hugh Dancy and musical guest Lyle Lovett and His Large Band.

Jon Hamm, Robbie Maddison, Adam Jones & Mike Mason, Cobra Starship feat. Estelle

The Tonight Show with Conan O'Brien welcomes actor Jon Hamm, freestyle motocross athletes Robbie Maddison, Adam Jones an

Gordon Ramsay, B.J. Novak, Willard Wigan

The Tonight Show with Conan O'Brien welcomes Chef/TV host Gordon Ramsay, actor BJ Novak and micro sculptor Willard Wigan

Robin Williams, Piers Morgan, All Time Low

The Tonight Show with Conan O'Brien welcomes Robin Williams, Piers Morgan and musical guests All Time Low.

Shaquille O'Neal, Demetri Martin, Jack Ingram

The Tonight Show with Conan O'Brien welcomes NBA superstar Shaquille O'Neil, comic Demitri Martin, and musical performan

Bill Maher, Nick Cannon, Kings of Leon

The Tonight Show with Conan O'Brien welcomes TV host Bill Maher, TV host Nick Cannon and musical guests Kings Of Leon. A

Quentin Tarantino, Mark Feuerstein, Smokey Robinson

The Tonight Show with Conan O'Brien welcomes film director Quentin Tarantino, actor Mark Feuerstein and musical guest Sm

Bradley Cooper, Franz Ferdinand

The Tonight Show with Conan O'Brien welcomes actor Bradley Cooper, actor/comedian Jon Lovitz and musical guests Franz Fe

Mike Tyson, Keith Barry, Matisyahu

The Tonight Show with Conan O'Brien welcomes boxing legend Mike Tyson, mentalist Keith Barry and musical guest Matisyahu

Nigel Marven, DJ Qualls, Colbie Caillat

The Tonight Show with Conan O'Brien welcomes reptile expert Nigel Marven, actor DJ Qualls and musical guest Colbie Caill

Norm Macdonald, Thomas Haden Church, Pitbull

The Tonight Show with Conan O'Brien welcomes comedian Norm MacDonald, actor Thomas Haden Church and musical guest Pitbul

Elijah Wood, Mila Kunis, Cheap Trick

The Tonight Show with Conan O'Brien welcomes actor Elijah Wood, actress Mila Kunis, and musical guests Cheap Trick.

Sen. John McCain, Frank Caliendo, Third Eye Blind

The Tonight Show with Conan O'Brien welcomes Senator John McCain, comedian Frank Caliendo, and musical guest Third Eye B

Sandra Bullock, The Little League World Series Champions, Gina Yashere

The Tonight Show with Conan O'Brien welcomes actress Sandra Bullock, Little League All-Stars from Chula Vista Park View,

Jennifer Connelly, Zane Lamprey, Ziggy Marley

The Tonight Show with Conan O'Brien welcomes actress Jennifer Connelly, actor/comedian Zane Lamprey, and musical guest Z

Kate Beckinsale, Richard Lewis, Dhani Harrison

The Tonight Show with Conan O'Brien welcomes actress Kate Beckinsale, comic/actor Richard Lewis, and guest Dhani Harriso

Tom Arnold, Tim Meadows, Reba McEntire

The Tonight Show with Conan O'Brien welcomes actor Tom Arnold, comedian Tim Meadows and musical guest Reba McEntire.

Dennis Quaid, Crossbow Marksmen, Paolo Nutini

The Tonight Show with Conan O'Brien welcomes actor Dennis Quaid, crossbow marksmen Mr. and Mrs. G, and musical guest Pao

Antonio Banderas, Bill Hader, Chris Cornell

The Tonight Show with Conan O'Brien welcomes actor Antonio Banderas, actor Bill Hader, and musical guest Chris Cornell.

Charlize Theron, Steven Ho, Dave Matthews Band

The Tonight Show with Conan O'Brien welcomes actress Charlize Theron, stuntman Steven Ho, and musical performance by Dav

Jennifer Aniston, Melanie Oudin, Phoenix

The Tonight Show with Conan O'Brien welcomes actress Jennifer Aniston, tennis player Melanie Oudin, and musical performa

Aaron Eckhart, Michael Strahan, Yeah Yeah Yeahs

The Tonight Show with Conan O'Brien welcomes actor Aaron Eckhart, former professional football player Michael Strahan, a

Megan Fox, Louis C.K., Kevin Skinner

The Tonight Show with Conan O'Brien welcomes actress Megan Fox, comedian Louis C.K. (who also performs) and musical gues

Courteney Cox, Ted Danson, Nelly Furtado

The Tonight Show with Conan O'Brien welcomes actress Courteney Cox, actor Ted Danson, and musical performance by Nelly F

Ricky Gervais, Chicken Charlie, Lynyrd Skynyrd

The Tonight Show with Conan O'Brien welcomes actor/comedian Ricky Gervais, fried-food innovator "Chicken" Charlie Boghos

Rebecca Romijn, Lisa Lampanelli, Monsters of Folk

The Tonight Show with Conan O'Brien welcomes actress Rebecca Romijn, comedian Lisa Lampanelli and musical guests Monster

Martin Short, Tim Gunn, Wynonna

The Tonight Show with Conan O'Brien welcomes actor Martin Short, fashion consultant Tim Gunn and musical guest Wynonna.

Dave Salmoni, Joel McHale, India.Arie

The Tonight Show welcomes animal expert Dave Salmoni, actor/presenter Joel McHale, and musical guest India Arie. Also, a

Drew Barrymore, jockey Joe Talamo, Paramore

The Tonight Show welcomes actress Drew Barrymore, jockey Joe Talamo and musical guests Paramore. Plus, Conan and Andy ta

Patton Oswalt, John Krasinski, Quinn Dahle

The Tonight Show welcomes actor John Krasinski, comedian Patton Oswalt and comedian Quinn Dahle. Also, the Hunky Vampire

Kate Walsh, Jesse Eisenberg, Brad Paisley

The Tonight Show welcomes actress Kate Walsh, actor Jesse Eisenberg and musical guest Brad Paisley. Also, back row appre

Michael Moore, Seth MacFarlane, Rodrigo y Gabriela

The Tonight Show welcomes director Michael Moore, animated series creator Seth MacFarlane and musical guests Rodrigo Y G

Drew Carey, Joe Buck, Joshua Bell with Tiempo Libre

The Tonight Show welcomes game show host Drew Carey, sportscaster Joe Buck, and musical guest Joshua Bell with Tiempo Li

Ellen Page, Kevin Nealon, Dierks Bentley

The Tonight Show welcomes actress Ellen Page, comedian Kevin Nealon, and musical guest Dierks Bentley. Plus, Conan answe

Edward Norton, Kristen Bell, Anvil

The Tonight Show with Conan O'Brien welcomes actor Edward Norton, actress Kristen Bell and musical guest Anvil. Also, a

Jason Bateman, Selena Gomez, Toby Keith

The Tonight Show with Conan O'Brien welcomes actor Jason Bateman, actress Selena Gomez and musical guest Toby Keith. Al

Christian Slater, Jimmie Johnson, the Backstreet Boys

The Tonight Show with Conan O'Brien welcomes actor Christian Slater, NASCAR driver Jimmie Johnson, and musical guests Ba

Jeff Garlin, Zack Hample, Lady Antebellum

The Tonight Show with Conan O'Brien welcomes comic actor Jeff Garlin, baseball snagger extraordinaire Zack Hample and mu

Jamie Foxx, Jason Alexander, Grizzly Bear

The Tonight Show with Conan O'Brien welcomes actor Jamie Foxx, actor Jason Alexander, and performance by Grizzly Bear.

Ice-T, Eddie Izzard, the Flaming Lips

The Tonight Show welcomes guests actor Ice-T, actor Eddie Izzard and musical guests Flaming Lips. Also, Conan shows a pr

Serena Williams, Ken Jeong, Rascal Flatts

The Tonight Show welcomes guest tennis player Serena Williams, actor Ken Jeong and musical guests Rascal Flatts. Also, n

John C. Reilly, Dr. Sanjay Gupta, Matt Braunger

The Tonight Show welcomes actor John C. Reilly, Dr. Sanjay Gupta and comedian Matt Braunger. Plus, the day before receiv

Newark Mayor Cory Booker, Max Records, Dashboard Confessional

The Tonight Show welcomes Newark Mayor Cory Booker, actor Max Records and musical guests Dashboard Confessional. Plus, T

Kathy Griffin, Capt. Chesley Sullenberger, Wolfmother

The Tonight Show with Conan O'Brien welcomes comic Kathy Griffin, Captain Chesley Sullenberger and musical guests Wolfmo

Garry Shandling, Paula Deen, Julian Casablancas

The Tonight Show with Conan O'Brien welcomes guest actor Garry Shandling, chef Paula Deen, and musical guests Julian Cas

Chris O'Donnell, Lindsey Vonn, Uncle Kracker

The Tonight Show with Conan O'Brien welcomes guests actor Chris O'Donnell, ski racer Lindsey Vonn, and musical performan

Denis Leary, Rob Mies, The Swell Season

The Tonight Show with Conan O'Brien welcomes guests actor Denis Leary, bat expert Rob Mies, and musical performance by T

Fri, Oct 30 2009

The Tonight Show with Conan O'Brien welcomes guests actor Ewan McGregor, snowboarder Shaun White, and a musical performa

Ewan McGregor, Shaun White, Tegan & Sara

The Tonight Show with Conan O'Brien welcomes guests actor Ewan McGregor, snowboarder Shaun White, and a musical performa

Neil Patrick Harris, Paul Teutul Sr., Creed

The Tonight Show with Conan O'Brien welcomes guests actor Neil Patrick Harris, TV personality Paul Teutul Sr., and a mus

Amy Poehler, Magic Johnson & Larry Bird, The Bravery

The Tonight Show with Conan O'Brien welcomes guest actress Amy Poehler, NBA Hall of Famers Magic Johnson and Larry Bird

Jim Carrey, Olivia Wilde, Zac Brown Band

The Tonight Show with Conan O'Brien welcomes guests actor Jim Carrey, actress Olivia Wilde, and a musical performance by

Cory Monteith, Harland Williams, Pixies

The Tonight Show with Conan O'Brien welcomes actor Cory Monteith, comedian Harland Williams and musical guests Pixies. A

Kelsey Grammer, Major Brian Dennis and his Iraqi dog of war Nubs, David Grey

The Tonight Show with Conan O'Brien welcomes actor Kelsey Grammer, Major Brian Dennis and his Iraqi dog of war Nubs, and

Jessica Biel, Super Dave Osborne, John Fogerty

The Tonight Show with Conan O'Brien welcomes actress Jessica Biel, comic Bob Einstein as Super Dave Osborne and musical

Heather Locklear, Dr. Drew Pinsky, Rodman

The Tonight Show with Conan O'Brien welcomes actress Heather Locklear, Dr. Drew Pinsky, and comedian guest Rodman. Also

Al Gore, Jim Parsons, Jason Mraz

The Tonight Show with Conan O'Brien welcomes former Vice President Al Gore, actor Jim Parsons, and musical guest Jason M

Reese Witherspoon, Gabourey Sidibe, Kris Allen

The Tonight Show with Conan O'Brien welcomes actress Reese Witherspoon, actress Gabourey Sidibe, and a musical performan

Kristen Stewart, Judd Apatow, Carrie Underwood

The Tonight Show with Conan O'Brien welcomes actress Kristen Stewart, director Judd Apatow and musical guest Carrie Unde

Jane Lynch, 50 Cent

The Tonight Show with Conan O'Brien welcomes actress Jane Lynch and musical guest 50 Cent.

Seth Green, Heidi Montag & Spencer Pratt, The Brian Setzer Orchestra

The Tonight Show with Conan O'Brien welcomes actor Seth Green, TV personalities Heidi Montag and Spencer Pratt and music

Nicole Kidman, Anderson Cooper, Leona Lewis

The Tonight Show with Conan O'Brien welcomes actress Nicole Kidman, journalist Anderson Cooper and musical guest Leona L

Eva Mendes, Jon Bon Jovi

The Tonight Show with Conan O'Brien welcomes actress Eva Mendes, musician Jon Bon Jovi and musical guests Bon Jovi.

Taylor Lautner, John Lovitz, Timbaland, Nelly Furtado, SoShy

The Tonight Show with Conan O'Brien welcomes actor Taylor Lautner, actor John Lovitz and musical guests Timbaland with N

Jack McBrayer, Marisa Miller, Weezer

The Tonight Show with Conan O'Brien welcomes actor Jack McBrayer, model Marisa Miller, and a musical performance by Weez

Norm MacDonald, Gretchen Bleiler, Dan Cummins

The Tonight Show with Conan O'Brien welcomes actor Norm MacDonald, snowboarder Gretchen Bleiler and comic Dan Cummins.

Pee Wee Herman, Donald Faison, Bon Jovi

The Tonight Show with Conan O'Brien welcomes Paul Reubens as Pee Wee Herman, actor Donald Faison and musical guests Bon

William Shatner, AnnaLynne McCord, cast of Mary Poppins

The Tonight Show with Conan O'Brien welcomes actor William Shatner, actress AnnaLynne McCord and a musical performance b

Tobey Maguire, Chris Colfer, Rickie Lee Jones

The Tonight Show with Conan O'Brien welcomes actor Tobey Maguire, actor Chris Colfer and musical guest Rickie Lee Jones.

Jenny McCarthy, Gabriel Iglesias

The Tonight Show with Conan O'Brien welcomes actress Jenny McCarthy and comedian Gabriel Iglesias.

John Travolta, Rod Stewart

The Tonight Show with Conan O'Brien welcomes guest actor John Travolta and guest singer Rod Stewart who also performs.

Rachel McAdams, Mindy Kaling, Diane Birch

The Tonight Show with Conan O'Brien welcomes actress Rachel McAdams, actress Mindy Kaling, and musical guest Diane Birch

Howie Mandel, Deepak Chopra, Michael McDonald

The Tonight Show with Conan O'Brien welcomes TV host Howie Mandel, doctor/author Deepak Chopra and musical guest Michael

Josh Brolin, Tillie the Dog Artist, Chad Daniels

The Tonight Show with Conan O'Brien welcomes actor Josh Brolin, Tillie the Dog Artist and comedian Chad Daniels.

Snoop Dogg, Carl Reiner

The Tonight Show with Conan O'Brien welcomes rapper Snoop Dogg, movie legend Carl Reiner and a musical performance by Sn

Ben Stiller, Michael Voltaggio, 30 Seconds To Mars

The Tonight Show with Conan O'Brien welcomes actor Ben Stiller, Top Chef winner Michael Voltaggio, and musical guests 30

Zach Braff, Bear Grylls, Tony Bennett

The Tonight Show with Conan O'Brien welcomes actor Zach Braff, adventurer Bear Grylls and musical guest Tony Bennett.

Tom Arnold, Cheryl Hines, Adam Lambert

The Tonight Show with Conan O'Brien welcomes actor Tom Arnold, actress Cheryl Hines and musical guest Adam Lambert. Plus

Megan Mullally,'The Situation' & 'Snooki' & Norah Jones

The Tonight Show with Conan O'Brien welcomes actress Megan Mullally, TV personalities Mike "The Situation" Sorrentino an

Wanda Sykes, James Cameron, Myq Kaplan

The Tonight Show with Conan O'Brien welcomes TV show host Wanda Sykes, director James Cameron and stand-up comedian Myq

John Krasinski, Claire Smith, Robin Thicke

The Tonight Show with Conan O'Brien welcomes guests actor John Krasinski, molecular mixologist Claire Smith, and a music

Sam Worthington, Nigel Marven, Foreigner

The Tonight Show with Conan O'Brien welcomes guests actor Sam Worthington, animal expert Nigel Marven, and a musical pe

Christina Applegate, David Gregory, Silversun Pickups

The Tonight Show with Conan O'Brien welcomes guests actress Christina Applegate, journalist David Gregory, and a musical

Lance Armstrong, Carson Daly, Kid Cudi

The Tonight Show with Conan O'Brien welcomes guests professional cyclist Lance Armstrong, TV show host Carson Daly, and

Elijah Wood, Derek Fisher, Dwayne Perkins

The Tonight Show with Conan O'Brien welcomes guests professional basketball player Derek Fisher.

Ethan Hawke, Patton Oswalt, Katharine McPhee

The Tonight Show with Conan O'Brien welcomes actor Ethan Hawke, comic Patton Oswalt and musical guest Katharine McPhee.

Queen Latifah, Chris Pratt, Juston McKinney

The Tonight Show with Conan O'Brien welcomes guests actress Queen Latifah, actor Chris Pratt, and comic Juston McKinney.

Matthew Broderick, Ke$ha

The Tonight Show with Conan O'Brien welcomes actor Matthew Broderick, actress Robin Tunney and musical guest Ke$ha. Also

Jackie Chan, Emily Blunt, Jencarlos

The Tonight Show with Conan O'Brien welcomes actor Jackie Chan, actress Emily Blunt and musical guest Jencarlos. Also,

Michael Cera, Aziz Ansari, OK Go

The Tonight Show with Conan O'Brien welcomes actor Michael Cera, actor and comedian Aziz Ansari and musical guests OK Go

Gary Oldman, Dax Shepard, Vampire Weekend

The Tonight Show with Conan O'Brien welcomes actor Gary Oldman, actor Dax Shepard and musical guests Vampire Weekend. Al

Tom Brokaw, Zachary Levi, Rosanne Cash

The Tonight Show with Conan O'Brien welcomes journalist Tom Brokaw, actor Zachary Levi and musical guest Rosanne Cash. P

Ricky Gervais, Bryce Dallas Howard, Whitney Cummings

The Tonight Show with Conan O'Brien welcomes actor Ricky Gervais, actress Bryce Dallas Howard, plus a performance by com

Rob Lowe, Jane Krakowski, Hilary Hahn

The Tonight Show with Conan O'Brien welcomes guests actor Rob Lowe, actress Jane Krakowski, and a musical performance by

Jeff Bridges, Mary Lynn Rajskub, Lifehouse

The Tonight Show with Conan O'Brien welcomes guests actor Jeff Bridges, actress Mary Lynn Rajskub, and a musical perform

Martin Scorsese, Colin Firth, Cirque du Soleil

The Tonight Show with Conan O'Brien welcomes movie director Martin Scorsese, actor Colin Firth and KOOZA - a Performance

Quentin Tarantino, Paul Bettany, Spoon

The Tonight Show with Conan O'Brien welcomes director Quentin Tarantino, actor Paul Bettany and musical guests Spoon.

Adam Sandler, Joel McHale, Joss Stone

The Tonight Show with Conan O'Brien welcomes actor Adam Sandler, actor Joel McHale and musical guest Joss Stone.

Robin Williams, Barry Manilow

The Tonight Show with Conan O'Brien welcomes actor Robin Williams and musical guest Barry Manilow.

Tom Hanks, Neil Young, Will Ferrell

The Tonight Show with Conan O'Brien welcomes actor Tom Hanks and actor Will Ferrell. This is the Final Episode with Co

Fri, Jan 22, 2010